PROTEIN DATABASE
- it is the archive of experimentally determined three dimensional structure of biological macro molecules that serves a global community of researchers, educators and students.
- the data obtained by X-ray crystallography or NMR spectroscopy and submitted by researchers to this website.
- the website is known as Protein Data Bank.
- it act as important resource for research in academic, pharmaceutical and biotechnology sectors.
RASMOL
- it is computer program written for interactive molecular graphics visualization intended and used primarily for the depiction and exploration of biological macromolecules structures.
- it is used in Protein Data Bank
- it reads in the 3-D coordinates for a molecule using pdf file format
- it allow one to rotate the molecule interactively
RENIN
Ketopiperazine-Based Renin Inhibitors: Optimization of the C Ring |
CLASSIFICATION : HYDROLASE
STRUCTURE WEIGHT : 74547.03
MOLECULE : RENIN
POLYMER : 1
TYPE : PROTEIN
LENGTH : 333
CHAINS : A, B
ORGANISM : HOMOSAPIEN
HTR A
HTR-like protein from Haloarcula marismortui |
CLASSIFICATION : TRANSFERASE
STRUCTURE WEIGHT : 60054.17
MOLECULE : HTR A
POLYMER : 1
TYPE : PROTEIN
LENGTH : 126
CHAINS : A, B, C, D
ORGANISM : HALOARCULA MARISMORTUI ATCC 43049
FRAGMENT PAS DOMAIN : RESIDUE 387 - 509 |
What is the meaning of this things???Let's explore about that now...yeaayyyy...There are many types of subtilisin enzyme,but today we only focused on 4C3U subtilisin.
For 4C3U,the discription of this molecular can be summarise as follow:
CLASSIFICATION : HYDROLASE
STRUCTURE WEIGHT : 28911.24
MOLECULE : SUBTILISIN CARLSBERG
POLYMER : 1
TYPE : PROTEIN
LENGTH : 274
DEGQ
Now,we proceed to the next enzyme which is DegQ.We choose 3PV5 DegQ to describe in this blog.
CLASSIFICATION : HYDROLASE
STRUCTURE WEIGHT : 28911.24
MOLECULE : SUBTILISIN CARLSBERG
POLYMER : 1
TYPE : PROTEIN
LENGTH : 274
CHAINS : A
EC# : 3.4.21.62
ORGANISM : BACCILUS LICHENIFORMIS
DEGQ
Now,we proceed to the next enzyme which is DegQ.We choose 3PV5 DegQ to describe in this blog.
The detail about enzyme 3PV5 can be summarise as follow :
CLASSIFICATION : HYDROLASE
STRUCTURE WEIGHT : 191744.00
MOLECULE : DegQ
POLYMER : 1
TYPE : PROTEIN
LENGTH : 451
MUTATION : N189G, P190G
ORGANISM : LEGIONELLA FALLONII
THERMOLYSIN
Our last enzyme for today is thermolysin 1KJO.Let's explore about this.
Same with previous structure,thermolysin 1KJO also have its own description.
CLASSIFICATION : HYDROLASE/HYDROLASE INHIBATOR
STRUCTURE WEIGHT : 34876.02
MOLECULE : THERMOLYSIN
POLYMER : 1
TYPE : PROTEIN
LENGTH : 316
EC# : 3.4.24.27
ORGANISM : BACILLUS THERMOPROTEOLYTICUS
GENE NAME : NPR